PLAP Antikörper (Biotin)

Produktnummer ABIN6155953

Produktdetails anti-PLAP Antikörper (Biotin)

Target: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PLAP Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Mouse Monoclonal anti-PLAP (Placental Alkaline Phosphatase) (ALPP/238), Biotin Conjugate

Produktmerkmale: PLAP is a tissue specific, trophoblast-derived, 70 kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2 metallo glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific AP's in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98 % homologous. Non-tissue specific AP is found in kidney, liver and bone. This MAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP as to AP from normal human testis. This MAb can be used both as coating as well as tracer antibody in the same ELISA to detect PLAP in serum of S, F, FS and I phenotypes. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human ALPP protein

Klon: ALPP-238

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Immunohistology frozen 1-2 μg/mL for 30 minutes at RT

• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

HepG2 cells. Placenta or seminoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu PLAP

Target: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Andere Bezeichnung: PLAP (Placental Alkaline Phosphatase) (ALPP Produkte)

Synonyme: ECK0378 antikoerper, JW0374 antikoerper, psiA antikoerper, ALP antikoerper, PALP antikoerper, PLAP antikoerper, PLAP-1 antikoerper, ILC antikoerper, CTACK antikoerper, ESkine antikoerper, Akp2 antikoerper, alp antikoerper, zgc:56672 antikoerper, DDBDRAFT_0205491 antikoerper, DDBDRAFT_0231570 antikoerper, DDB_0205491 antikoerper, DDB_0231570 antikoerper, ALPI antikoerper, Actn2lp antikoerper, Alp antikoerper, bacterial alkaline phosphatase antikoerper, alkaline phosphatase, placental antikoerper, alkaline phosphatase, placental type antikoerper, C-C motif chemokine ligand 27 antikoerper, alkaline phosphatase, liver/bone/kidney antikoerper, alkaline phosphatase antikoerper, alkaline phosphatase, intestinal antikoerper, PDZ and LIM domain 3 antikoerper, phoA antikoerper, ALPP antikoerper, LOC100436725 antikoerper, CCL27 antikoerper, alpl antikoerper, alp antikoerper, ALPI antikoerper, Pdlim3 antikoerper, Alpp antikoerper

Molekulargewicht: 70 kDa

Gen-ID: 250, 284255

UniProt: P05187