MLL4 Antikörper (C-Term)

Produktnummer ABIN614966

Produktdetails anti-MLL4 Antikörper

Target: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MLL4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: CNCGAKRCRR FLN

Spezifität: This antibody detects MLL4 (C-term).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity chromatography

Immunogen: Synthetic peptide from C-term of human MLL4 Genename: MLL4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MLL4

Target: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Andere Bezeichnung: MLL4 (MLL4 Produkte)

Synonyme: HRX2 antikoerper, MLL1B antikoerper, MLL2 antikoerper, MLL4 antikoerper, TRX2 antikoerper, WBP7 antikoerper, 2610014H22Rik antikoerper, Mll2 antikoerper, Wbp7 antikoerper, mKIAA0304 antikoerper, ALR antikoerper, BC032281 antikoerper, BC058659 antikoerper, C430014K11Rik antikoerper, KMT2B antikoerper, Mll4 antikoerper, RGD1308331 antikoerper, lysine methyltransferase 2B antikoerper, lysine (K)-specific methyltransferase 2B antikoerper, lysine (K)-specific methyltransferase 2D antikoerper, KMT2B antikoerper, Kmt2b antikoerper, Kmt2d antikoerper

Hintergrund: This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.Synonyms: HRX2, Histone-lysine N-methyltransferase MLL4, KIAA0304, KMT2D, Lysine N-methyltransferase 2D, MLL2, Myeloid/lymphoid or mixed-lineage leukemia protein 4, TRX2, Trithorax homolog 2, WBP7, WW domain-binding protein 7

Gen-ID: 9757

NCBI Accession: NP_055542

UniProt: Q9UMN6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effekt