MLL4 Antikörper (N-Term)

Produktnummer ABIN2778080

Der Kaninchen Polyklonal anti-MLL4 Antikörper (ABIN2778080) detektiert spezifisch MLL4 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Saccharomyces cerevisiae.

Kurzübersicht für MLL4 Antikörper (N-Term) (ABIN2778080)

Target: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MLL4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MLL4 Antibody - N-terminal region

Sequenz: WAGPRVQRGR GRGRGRGWGP SRGCVPEEES SDGESDEEEF QGFHSDEDVA

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 92%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Yeast: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against MLL4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MLL4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8102627

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MLL4

Target: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Andere Bezeichnung: MLL4

Hintergrund:

Background Information: MLL4 a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. MLL4 is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer

Gene Name: Myeloid/lymphoid or mixed-lineage leukemia 4

Alternative Symbols: HRX2, MLL2, MLL4, TRX2, WBP7, DYT28, MLL1B, WBP-7, CXXC10

Protein Name: Histone-lysine N-methyltransferase MLL4

Molekulargewicht: 64kDa

Gen-ID: 9757

UniProt: Q9UMN6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effekt