TNFRSF4 Antikörper (AA 29-214)

Produktnummer ABIN6149325

Produktdetails anti-TNFRSF4 Antikörper

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Bindungsspezifität: AA 29-214

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LHCVGDTYPS NDRCCHECRP GNGMVSRCSR SQNTVCRPCG PGFYNDVVSS KPCKPCTWCN LRSGSERKQL CTATQDTVCR CRAGTQPLDS YKPGVDCAPC PPGHFSPGDN QACKPWTNCT LAGKHTLQPA SNSSDAICED RDPPATQPQE TQGPPARPIT VQPTEAWPRT SQGPSTRPVE VPGGRA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-214 of human OX40 (NP_003318.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TNFRSF4

Target: TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))

Andere Bezeichnung: TNFRSF4 (TNFRSF4 Produkte)

Synonyme: TNFRSF4 antikoerper, ACT35 antikoerper, CD134 antikoerper, Ly-70 antikoerper, Ox40 antikoerper, TXGP1L antikoerper, Txgp1 antikoerper, OX40 antikoerper, TNF receptor superfamily member 4 antikoerper, tumor necrosis factor receptor superfamily, member 4 antikoerper, TNFRSF4 antikoerper, Tnfrsf4 antikoerper

Hintergrund: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.,TNFRSF4,ACT35,CD134,IMD16,OX40,TXGP1L,Immunology & Inflammation,CD markers,Cytokines,TNF,NF-kB Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Stem Cells,Hematopoietic Progenitors,TNFRSF4

Molekulargewicht: 29 kDa

Gen-ID: 7293

UniProt: P43489

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints