TNFRSF4 Antikörper (AA 29-214)
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- Target Alle TNFRSF4 Antikörper anzeigen
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
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Bindungsspezifität
- AA 29-214
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TNFRSF4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human OX40 (AA: extra 29-214) expressed in HEK293 cells.
- Klon
- 7B5E10
- Isotyp
- IgG2a
- Top Product
- Discover our top product TNFRSF4 Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
- Andere Bezeichnung
- OX40 (TNFRSF4 Produkte)
- Synonyme
- TNFRSF4 antikoerper, ACT35 antikoerper, CD134 antikoerper, Ly-70 antikoerper, Ox40 antikoerper, TXGP1L antikoerper, Txgp1 antikoerper, OX40 antikoerper, TNF receptor superfamily member 4 antikoerper, tumor necrosis factor receptor superfamily, member 4 antikoerper, TNFRSF4 antikoerper, Tnfrsf4 antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Aliases: TNFRSF4, ACT35, CD134, IMD16, TXGP1L
- Molekulargewicht
- 29.3 kDa
- Gen-ID
- 7293
- HGNC
- 7293
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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