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TNFRSF4 Antikörper (AA 29-214)

TNFRSF4 Reaktivität: Human WB, FACS, ELISA, IHC, ICC, Neut Wirt: Maus Monoclonal 7B5E10 unconjugated
Produktnummer ABIN5611188
  • Target Alle TNFRSF4 Antikörper anzeigen
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    Bindungsspezifität
    • 15
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-214
    Reaktivität
    • 68
    • 53
    • 34
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 56
    • 37
    • 17
    • 2
    Maus
    Klonalität
    • 57
    • 53
    Monoklonal
    Konjugat
    • 54
    • 12
    • 11
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TNFRSF4 Antikörper ist unkonjugiert
    Applikation
    • 60
    • 53
    • 31
    • 15
    • 14
    • 13
    • 12
    • 11
    • 10
    • 8
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human OX40 (AA: extra 29-214) expressed in HEK293 cells.
    Klon
    7B5E10
    Isotyp
    IgG2a
    Top Product
    Discover our top product TNFRSF4 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    Andere Bezeichnung
    OX40 (TNFRSF4 Produkte)
    Synonyme
    TNFRSF4 antikoerper, ACT35 antikoerper, CD134 antikoerper, Ly-70 antikoerper, Ox40 antikoerper, TXGP1L antikoerper, Txgp1 antikoerper, OX40 antikoerper, TNF receptor superfamily member 4 antikoerper, tumor necrosis factor receptor superfamily, member 4 antikoerper, TNFRSF4 antikoerper, Tnfrsf4 antikoerper
    Hintergrund

    Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

    Aliases: TNFRSF4, ACT35, CD134, IMD16, TXGP1L

    Molekulargewicht
    29.3 kDa
    Gen-ID
    7293
    HGNC
    7293
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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