TNFRSF12A Antikörper (AA 28-129)

Produktnummer ABIN6149315

Produktdetails anti-TNFRSF12A Antikörper

Target: TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))

Bindungsspezifität: AA 28-129

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF12A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWPILGGALS LTFVLGLLSG FLVWRRCRRR EKFTTPIEET GGEGCPAVAL IQ

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-129 of human TWEAKR/Fn14/CD266 (NP_057723.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TNFRSF12A

Target: TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))

Andere Bezeichnung: TNFRSF12A (TNFRSF12A Produkte)

Synonyme: CD266 antikoerper, FN14 antikoerper, TWEAKR antikoerper, AI255180 antikoerper, C87282 antikoerper, Fn14 antikoerper, HPIP antikoerper, TWEAK-R antikoerper, TweakR antikoerper, TNF receptor superfamily member 12A antikoerper, tumor necrosis factor receptor superfamily, member 12a antikoerper, TNFRSF12A antikoerper, Tnfrsf12a antikoerper

Hintergrund: Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Human and mouse TNFRSF12A share 82 % aa sequence identity. TNFRSF12A transcript was expressed at high levels in heart, placenta, and kidney, at intermediate levels in lung, skeletal muscle, and pancreas, and at low levels in brain and liver. In addition, elevated TNFRSF12A expression was found in human liver cancer cell lines and hepatocellular carcinoma specimens. TNFRSF12A is the weak inducer of apoptosis in some cell types. It promotes angiogenesis and the proliferation of endothelial cells. TNFRSF12A may modulate cellular adhesion to matrix proteins.,TNFRSF12A,CD266,FN14,TWEAKR,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TNF,Immunology & Inflammation,CD markers,NF-kB Signaling Pathway,Cardiovascular,Angiogenesis,TNFRSF12A

Molekulargewicht: 10 kDa/13 kDa

Gen-ID: 51330

UniProt: Q9NP84

Pathways: Apoptose, Regulation of Cell Size