RELB Antikörper (AA 380-579)
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- Target Alle RELB Antikörper anzeigen
- RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))
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Bindungsspezifität
- AA 380-579
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RELB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- FLQRLTDGVC SEPLPFTYLP RDHDSYGVDK KRKRGMPDVL GELNSSDPHG IESKRRKKKP AILDHFLPNH GSGPFLPPSA LLPDPDFFSG TVSLPGLEPP GGPDLLDDGF AYDPTAPTLF TMLDLLPPAP PHASAVVCSG GAGAVVGETP GPEPLTLDSY QAPGPGDGGT ASLVGSNMFP NHYREAAFGG GLLSPGPEAT
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 380-579 of human RELB (NP_006500.2).
- Isotyp
- IgG
- Top Product
- Discover our top product RELB Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- RELB (V-Rel Reticuloendotheliosis Viral Oncogene Homolog B (RELB))
- Andere Bezeichnung
- RELB (RELB Produkte)
- Synonyme
- shep antikoerper, I-REL antikoerper, IREL antikoerper, REL-B antikoerper, XRelB antikoerper, relb-A antikoerper, GC-rich antikoerper, avian reticuloendotheliosis viral (v-rel) oncogene related B antikoerper, RELB proto-oncogene, NF-kB subunit antikoerper, v-rel avian reticuloendotheliosis viral oncogene homolog B S homeolog antikoerper, Relb antikoerper, RELB antikoerper, relb.S antikoerper
- Hintergrund
- NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. RELB neither associates with DNA nor with RELA/p65 or REL. Stimulates promoter activity in the presence of NFKB2/p49. Increased repression of the heterodimer is seen in the presence of NFKB2/p52. Is required for both T and B lymphocyte maturation and function.,RELB,I-REL,IREL,REL-B,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,RELB
- Molekulargewicht
- 62 kDa
- Gen-ID
- 5971
- UniProt
- Q01201
- Pathways
- NF-kappaB Signalweg, RTK Signalweg
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