POLD3 Antikörper (AA 197-466)

Produktnummer ABIN6145881

Produktdetails anti-POLD3 Antikörper

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Bindungsspezifität: AA 197-466

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: ASKAAAKTQE TNKETKTEAK EVTNASAAGN KAPGKGNMMS NFFGKAAMNK FKVNLDSEQA VKEEKIVEQP TVSVTEPKLA TPAGLKKSSK KAEPVKVLQK EKKRGKRVAL SDDETKETEN MRKKRRRIKL PESDSSEDEV FPDSPGAYEA ESPSPPPPPS PPLEPVPKTE PEPPSVKSSS GENKRKRKRV LKSKTYLDGE GCIVTEKVYE SESCTDSEEE LNMKTSSVHR PPAMTVKKEP REERKGPKKG TAALGKANRQ VSITGFFQRK

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 197-466 of human POLD3 (NP_006582.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-POLD3 Antikörper (ABIN6145881)

Xiang, Laurent, Hsu, Nachtergaele, Lu, Sheng, Xu, Chen, Ouyang, Wang, Ling, Hsu, Zou, Jambhekar, He, Shi: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).

Details zu POLD3

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Andere Bezeichnung: POLD3 (POLD3 Produkte)

Synonyme: zgc:136471 antikoerper, P66 antikoerper, P68 antikoerper, 2410142G14Rik antikoerper, C85233 antikoerper, polymerase (DNA-directed), delta 3, accessory subunit L homeolog antikoerper, polymerase (DNA-directed), delta 3, accessory subunit antikoerper, DNA polymerase delta 3, accessory subunit antikoerper, pold3.L antikoerper, pold3 antikoerper, POLD3 antikoerper, Pold3 antikoerper

Hintergrund: This gene encodes the 66- kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene.,POLD3,P66,P68,PPP1R128,Epigenetics & Nuclear Signaling,DNA Damage & Repair,POLD3

Molekulargewicht: 39 kDa/46 kDa/51 kDa

Gen-ID: 10714

UniProt: Q15054

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA