RAD51 Antikörper

Produktnummer ABIN614571

Produktdetails anti-RAD51 Antikörper

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RAD51 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Recognizes RAD51

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein G Chromatography

Immunogen: Recombinant Human Rad51 protein.

Klon: 1-30E-005

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.2 without preservatives

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RAD51

Target: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Andere Bezeichnung: RAD51 (RAD51 Produkte)

Synonyme: BRCC5 antikoerper, HRAD51 antikoerper, HsRad51 antikoerper, HsT16930 antikoerper, MRMV2 antikoerper, RAD51A antikoerper, RECA antikoerper, CRAD51 antikoerper, wu:fb38e12 antikoerper, zgc:77754 antikoerper, RGD1563603 antikoerper, ATRAD51 antikoerper, F22D1.20 antikoerper, F22D1_20 antikoerper, RAS associated with diabetes protein 51 antikoerper, AV304093 antikoerper, Rad51a antikoerper, Reca antikoerper, brcc5 antikoerper, rad51 antikoerper, rad51a antikoerper, reca antikoerper, xrad51 antikoerper, RAD51 recombinase antikoerper, RAS associated with diabetes protein 51 antikoerper, RAD51 recombinase L homeolog antikoerper, RAD51 antikoerper, rad51 antikoerper, Rad51 antikoerper, rad51.L antikoerper

Hintergrund: Rad51, a 37 kDa protein, is the human homologue of E. coli RecA protein and a member of the RAD52 epistasis group in S. cerevisiae. In recent studies it has been reported that BRCA1 interacts with Rad51 and disease-causing mutations have been found in the BRCA1 region necessary for BRCA1/Rad51 interaction, implying that this interaction is important for tumor suppression. BRCA2 and Rad51 have also been shown to interact by direct binding of the BRC repeats located within exon 11 of BRCA2. When these repeats are deleted, the interaction is lost and cells become hypersensitive to the DNA damage caused by methyl methanesulfonate (MMS).Synonyms: DNA repair protein RAD51 homolog 1, RAD51A, RECA

Gen-ID: 5888

NCBI Accession: NP_002866

UniProt: Q06609

Pathways: DNA Reparatur