KCNQ2 Antikörper (AA 254-393)

Produktnummer ABIN6142772

Produktdetails anti-KCNQ2 Antikörper

Target: KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))

Bindungsspezifität: AA 254-393

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNQ2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EKGENDHFDT YADALWWGLI TLTTIGYGDK YPQTWNGRLL AATFTLIGVS FFALPAGILG SGFALKVQEQ HRQKHFEKRR NPAAGLIQSA WRFYATNLSR TDLHSTWQYY ERTVTVPMYR YRRRAPATKQ LFHFLFSICS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 254-393 of human KCNQ2 (NP_742107.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KCNQ2

Target: KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))

Andere Bezeichnung: KCNQ2 (KCNQ2 Produkte)

Synonyme: BFNC antikoerper, BFNS1 antikoerper, EBN antikoerper, EBN1 antikoerper, EIEE7 antikoerper, ENB1 antikoerper, HNSPC antikoerper, KCNA11 antikoerper, KV7.2 antikoerper, KVEBN1 antikoerper, KQT2 antikoerper, Nmf134 antikoerper, mKQT2.3 antikoerper, mKQT2.4 antikoerper, zgc:171872 antikoerper, potassium voltage-gated channel subfamily Q member 2 antikoerper, potassium voltage-gated channel, subfamily Q, member 2 antikoerper, potassium voltage-gated channel subfamily KQT member 2 antikoerper, potassium voltage-gated channel, KQT-like subfamily, member 2a antikoerper, KCNQ2 antikoerper, Kcnq2 antikoerper, LOC100537363 antikoerper, kcnq2a antikoerper

Hintergrund: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.,KCNQ2,BFNC,EBN,EBN1,ENB1,HNSPC,KCNA11,KV7.2,Neuroscience,Neurodegenerative Diseases,KCNQ2

Molekulargewicht: 44 kDa/92 kDa/93 kDa/94 kDa/95 kDa

Gen-ID: 3785

UniProt: O43526