Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

KCNQ2 Antikörper (N-Term)

KCNQ2 Reaktivität: Ratte, Human, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776303
  • Target Alle KCNQ2 Antikörper anzeigen
    KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
    Bindungsspezifität
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 30
    • 19
    • 14
    • 11
    • 10
    • 6
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    Ratte, Human, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 34
    • 1
    Kaninchen
    Klonalität
    • 35
    Polyklonal
    Konjugat
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCNQ2 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 15
    • 13
    • 13
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    IDIMVLIASI AVLAAGSQGN VFATSALRSL RFLQILRMIR MDRRGGTWKL
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against KCNQ2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human KCNQ2
    Top Product
    Discover our top product KCNQ2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 393 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KCNQ2 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 2 (KCNQ2))
    Andere Bezeichnung
    KCNQ2 (KCNQ2 Produkte)
    Synonyme
    BFNC antikoerper, BFNS1 antikoerper, EBN antikoerper, EBN1 antikoerper, EIEE7 antikoerper, ENB1 antikoerper, HNSPC antikoerper, KCNA11 antikoerper, KV7.2 antikoerper, KVEBN1 antikoerper, KQT2 antikoerper, Nmf134 antikoerper, mKQT2.3 antikoerper, mKQT2.4 antikoerper, zgc:171872 antikoerper, potassium voltage-gated channel subfamily Q member 2 antikoerper, potassium voltage-gated channel, subfamily Q, member 2 antikoerper, potassium voltage-gated channel subfamily KQT member 2 antikoerper, potassium voltage-gated channel, KQT-like subfamily, member 2a antikoerper, KCNQ2 antikoerper, Kcnq2 antikoerper, LOC100537363 antikoerper, kcnq2a antikoerper
    Hintergrund
    The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.
    Alias Symbols: BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, KV7.2, KVEBN1, BFNS1, EIEE7
    Protein Interaction Partner: ARIH2, KCNQ3, PRKCA, CALM3, CALM1, CALM2, KCNQ1,
    Protein Size: 393
    Molekulargewicht
    44 kDa
    Gen-ID
    3785
    NCBI Accession
    NM_172109, NP_742107
    UniProt
    Q53Y30
Sie sind hier:
Kundenservice