ITPR3 Antikörper (AA 1630-1870)

Produktnummer ABIN6142616

Produktdetails anti-ITPR3 Antikörper

Target: ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))

Bindungsspezifität: AA 1630-1870

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITPR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: EGSEAYQRCE SGGFLSKLIQ HTKDLMESEE KLCIKVLRTL QQMLLKKTKY GDRGNQLRKM LLQNYLQNRK STSRGDLPDP IGTGLDPDWS AIAATQCRLD KEGATKLVCD LITSTKNEKI FQESIGLAIH LLDGGNTEIQ KSFHNLMMSD KKSERFFKVL HDRMKRAQQE TKSTVAVNMN DLGSQPHEDR EPVDPTTKGR VASFSIPGSS SRYSLGPSLR RGHEVSERVQ SSEMGTSVLI M

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1630-1870 of human ITPR3 (NP_002215.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ITPR3

Target: ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))

Andere Bezeichnung: ITPR3 (ITPR3 Produkte)

Synonyme: Ip3r3 antikoerper, Itpr-3 antikoerper, IP3R antikoerper, IP3R3 antikoerper, IP3R3X antikoerper, inositol 1,4,5-triphosphate receptor 3 antikoerper, inositol 1,4,5-trisphosphate receptor type 3 antikoerper, inositol 1,4,5-trisphosphate receptor, type 3 antikoerper, Itpr3 antikoerper, ITPR3 antikoerper

Hintergrund: This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.,ITPR3,IP3R,IP3R3,Signal Transduction,Phospholipase Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,Neurodegenerative Diseases,ITPR3

Molekulargewicht: 304 kDa

Gen-ID: 3710

UniProt: Q14573

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, BCR Signaling