Fibronectin 1 Antikörper (AA 1-128)

Produktnummer ABIN6140725

Produktdetails anti-Fibronectin 1 Antikörper

Target: Fibronectin 1 (FN1)

Bindungsspezifität: AA 1-128

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibronectin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MLRGPGPGLL LLAVQCLGTA VPSTGASKSK RQAQQMVQPQ SPVAVSQSKP GCYDNGKHYQ INQQWERTYL GNALVCTCYG GSRGFNCESK PEAEETCFDK YTGNTYRVGD TYERPKDSMI WDCTCIGA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human Fibronectin (NP_002017.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-Fibronectin 1 Antikörper (ABIN6140725)

Xie, Zhang, Wang, Zhao, Zhang, Yao, Hur, Yeh, Pang, Zheng, Fan, Kong, Wang, Chiu, Zhou: "Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo: Role of DNA methyltransferase 1." in: Biomaterials, Vol. 155, pp. 203-216, (2018) (PubMed).

Cai, Ma, Xiao, Wu, Li, Liu, Qiu, Zhang: "High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway." in: Toxicology and applied pharmacology, Vol. 333, pp. 1-9, (2017) (PubMed).

Details zu Fibronectin 1

Target: Fibronectin 1 (FN1)

Andere Bezeichnung: FN1 (FN1 Produkte)

Synonyme: FN1 antikoerper, FN antikoerper, cig antikoerper, fibronectin antikoerper, finc antikoerper, lets antikoerper, msf antikoerper, Fn antikoerper, fn2 antikoerper, fb80d10 antikoerper, wu:fb80d10 antikoerper, CIG antikoerper, ED-B antikoerper, FINC antikoerper, FNZ antikoerper, GFND antikoerper, GFND2 antikoerper, LETS antikoerper, MSF antikoerper, E330027I09 antikoerper, Fn-1 antikoerper, FIBNEC antikoerper, fn-1 antikoerper, fibronectin 1 antikoerper, fibronectin 1a antikoerper, fibronectin 1 S homeolog antikoerper, FN1 antikoerper, fn1 antikoerper, fn1a antikoerper, Fn1 antikoerper, fn1.S antikoerper

Hintergrund: This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.,FN1,CIG,ED-B,FINC,FN,FNZ,GFND,GFND2,LETS,MSF,fibronectin,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Stem Cells,Mesenchymal Stem Cells,Neural Stem Cells,Cardiovascular,Angiogenesis,FN1

Molekulargewicht: 71-73 kDa/221-272 kDa

Gen-ID: 2335

UniProt: P02751

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie