DFFA Antikörper (AA 1-331)
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- Target Alle DFFA Antikörper anzeigen
- DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
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Bindungsspezifität
- AA 1-331
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DFFA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- MEVTGDAGVP ESGEIRTLKP CLLRRNYSRE QHGVAASCLE DLRSKACDIL AIDKSLTPVT LVLAEDGTIV DDDDYFLCLP SNTKFVALAS NEKWAYNNSD GGTAWISQES FDVDETDSGA GLKWKNVARQ LKEDLSSIIL LSEEDLQMLV DAPCSDLAQE LRQSCATVQR LQHTLQQVLD QREEVRQSKQ LLQLYLQALE KEGSLLSKQE ESKAAFGEEV DAVDTGISRE TSSDVALASH ILTALREKQA PELSLSSQDL ELVTKEDPKA LAVALNWDIK KTETVQEACE RELALRLQQT QSLHSLRSIS ASKASPPGDL QNPKRARQDP T
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human DFFA (NP_004392.1).
- Isotyp
- IgG
- Top Product
- Discover our top product DFFA Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:100
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
- Andere Bezeichnung
- DFFA (DFFA Produkte)
- Synonyme
- DFF-45 antikoerper, DFF1 antikoerper, ICAD antikoerper, A330085O09Rik antikoerper, DFF35 antikoerper, Dff45 antikoerper, ICAD-L antikoerper, ICAD-S antikoerper, DFFA antikoerper, zgc:92229 antikoerper, DNA fragmentation factor subunit alpha antikoerper, DNA fragmentation factor, alpha subunit antikoerper, DNA fragmentation factor, 45kDa, alpha polypeptide antikoerper, DNA fragmentation factor, alpha polypeptide antikoerper, DFFA antikoerper, Dffa antikoerper, dffa antikoerper
- Hintergrund
- Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,DFFA,DFF-45,DFF1,ICAD,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Death Receptor Signaling Pathway,Endocrine & Metabolism,DFFA
- Molekulargewicht
- 29 kDa/36 kDa
- Gen-ID
- 1676
- UniProt
- O00273
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
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