ARHGEF3 Antikörper (AA 287-526)
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- Target Alle ARHGEF3 Antikörper anzeigen
- ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
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Bindungsspezifität
- AA 287-526
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ARHGEF3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LEEAINIIQG IVAEINTKTG ESECRYYKER LLYLEEGQKD SLIDSSRVLC CHGELKNNRG VKLHVFLFQE VLVITRAVTH NEQLCYQLYR QPIPVKDLLL EDLQDGEVRL GGSLRGAFSN NERIKNFFRV SFKNGSQSQT HSLQANDTFN KQQWLNCIRQ AKETVLCAAG QAGVLDSEGS FLNPTTGSRE LQGETKLEQM DQSDSESDCS MDTSEVSLDC ERMEQTDSSC GNSRHGESNV
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 287-526 of human ARHGEF3 (NP_062455.1).
- Isotyp
- IgG
- Top Product
- Discover our top product ARHGEF3 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
- Andere Bezeichnung
- ARHGEF3 (ARHGEF3 Produkte)
- Synonyme
- MGC82822 antikoerper, ARHGEF3 antikoerper, si:ch211-258l4.8 antikoerper, MGC108040 antikoerper, DKFZp459N027 antikoerper, GEF3 antikoerper, STA3 antikoerper, XPLN antikoerper, 1200004I24Rik antikoerper, 9830169H03Rik antikoerper, C76747 antikoerper, Xpln antikoerper, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog antikoerper, Rho guanine nucleotide exchange factor 3 antikoerper, Rho guanine nucleotide exchange factor (GEF) 3 antikoerper, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 antikoerper, arhgef3.1.S antikoerper, ARHGEF3 antikoerper, arhgef3 antikoerper, arhgef3.1 antikoerper, Arhgef3 antikoerper
- Hintergrund
- Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,ARHGEF3,GEF3,STA3,XPLN,ARHGEF3
- Molekulargewicht
- 36 kDa/59 kDa/60 kDa/63 kDa
- Gen-ID
- 50650
- UniProt
- Q9NR81
- Pathways
- Neurotrophin Signalübertragung
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