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ARHGEF3 Produkte

(rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))

Kategorien

Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte ARHGEF3 Kategorien

ARHGEF3 Antikörper

High quality antibodies with extensive validation data.

ARHGEF3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ARHGEF3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN652003
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA
Validierungen
  • (2)
Kat. Nr. ABIN7167981
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN565494
Menge 50 μL
Datenblatt Datenblatt

Empfohlene ARHGEF3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345551
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345553
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3089362
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ARHGEF3 Produkten

Liu, Zheng, Cai, Guo, Lin, Chen, Liao, Kung, Zeng, Xie: "The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." in: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).

DAmato, DellAversana, Conte, Ciotta, Scisciola, Carissimo, Nebbioso, Altucci: "ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias." in: Epigenetics : official journal of the DNA Methylation Society, Vol. 10, Issue 1, pp. 6-18, (2015) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Synonyme und alternative Namen zu ARHGEF3

Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog (arhgef3.1.S), Rho guanine nucleotide exchange factor 3 (ARHGEF3), Rho guanine nucleotide exchange factor (GEF) 3 (arhgef3), Rho guanine nucleotide exchange factor (GEF) 3, gene 1 (arhgef3.1), Rho guanine nucleotide exchange factor (GEF) 3 (ARHGEF3), Rho guanine nucleotide exchange factor (GEF) 3 (Arhgef3), Rho guanine nucleotide exchange factor 3 (Arhgef3), 1200004I24Rik, 9830169H03Rik, ARHGEF3, C76747, DKFZp459N027, GEF3, MGC82822, MGC108040, si:ch211-258l4.8, STA3, XPLN, Xpln

Bezeichner auf Proteinebene für ARHGEF3

  • Rho guanine nucleotide exchange factor (GEF) 3
  • Rho guanine nucleotide exchange factor 3
  • rho guanine nucleotide exchange factor 3
  • rho guanine nucleotide exchange factor 3-like
  • 59.8 kDA protein
  • RhoGEF protein
  • exchange factor found in platelets and leukemic and neuronal tissues, XPLN
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