ARHGEF3 Antikörper

Produktnummer ABIN7264537

Produktdetails anti-ARHGEF3 Antikörper

Target: ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human ARHGEF3 (NP_062455.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ARHGEF3

Target: ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))

Andere Bezeichnung: ARHGEF3 (ARHGEF3 Produkte)

Synonyme: MGC82822 antikoerper, ARHGEF3 antikoerper, si:ch211-258l4.8 antikoerper, MGC108040 antikoerper, DKFZp459N027 antikoerper, GEF3 antikoerper, STA3 antikoerper, XPLN antikoerper, 1200004I24Rik antikoerper, 9830169H03Rik antikoerper, C76747 antikoerper, Xpln antikoerper, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog antikoerper, Rho guanine nucleotide exchange factor 3 antikoerper, Rho guanine nucleotide exchange factor (GEF) 3 antikoerper, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 antikoerper, arhgef3.1.S antikoerper, ARHGEF3 antikoerper, arhgef3 antikoerper, arhgef3.1 antikoerper, Arhgef3 antikoerper

Hintergrund: Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 60 kDa

Calculated_MW: 36 kDa/59 kDa/60 kDa/63 kDa

Gen-ID: 50650

UniProt: Q9NR81

Pathways: Neurotrophin Signalübertragung