ACVR1 Antikörper (AA 20-125)
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- Target Alle ACVR1 (ACRV1) Antikörper anzeigen
- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
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Bindungsspezifität
- AA 20-125
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ACVR1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SMEDEKPKVN PKLYMCVCEG LSCGNEDHCE GQQCFSSLSI NDGFHVYQKG CFQVYEQGKM TCKTPPSPGQ AVECCQGDWC NRNITAQLPT KGKSFPGTQN FHLEVG
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-125 of human ACVR1 (NP_001096.1).
- Isotyp
- IgG
- Top Product
- Discover our top product ACRV1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
- Andere Bezeichnung
- ACVR1 (ACRV1 Produkte)
- Synonyme
- ACTRI antikoerper, ACVR1A antikoerper, ACVRLK2 antikoerper, ALK2 antikoerper, FOP antikoerper, SKR1 antikoerper, TSRI antikoerper, ActR-IA antikoerper, ActR-I antikoerper, ActRIA antikoerper, Acvr antikoerper, Acvrlk2 antikoerper, Alk-2 antikoerper, Alk8 antikoerper, D330013D15Rik antikoerper, Tsk7L antikoerper, actri antikoerper, acvr1 antikoerper, acvr1-a antikoerper, acvr1-b antikoerper, acvr1a antikoerper, acvrlk2 antikoerper, alk-2 antikoerper, alk2 antikoerper, alk8 antikoerper, fop antikoerper, sax antikoerper, skr1 antikoerper, tsri antikoerper, xALK-2 antikoerper, activin A receptor type 1 antikoerper, activin A receptor, type 1 antikoerper, activin A receptor type 1 S homeolog antikoerper, ACVR1 antikoerper, Acvr1 antikoerper, acvr1.S antikoerper
- Hintergrund
- Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.,ACVR1,ACTRI,ACVR1A,ACVRLK2,ALK2,FOP,SKR1,TSRI,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,Extracellular Matrix,Bone,Stem Cells,Cardiovascular,Angiogenesis,ACVR1
- Molekulargewicht
- 57 kDa
- Gen-ID
- 90
- UniProt
- Q04771
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