ACVR1 Antikörper (AA 132-162)

Produktnummer ABIN3029855

Produktdetails anti-ACVR1 Antikörper

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Bindungsspezifität: AA 132-162

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACVR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat, Bovine

Aufreinigung: Purified

Immunogen: A portion of amino acids 132-162 from the human protein was used as the immunogen for this ALK2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the ALK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the ALK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu ACVR1

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Andere Bezeichnung: ALK2 (ACRV1 Produkte)

Synonyme: ACTRI antikoerper, ACVR1A antikoerper, ACVRLK2 antikoerper, ALK2 antikoerper, FOP antikoerper, SKR1 antikoerper, TSRI antikoerper, ActR-IA antikoerper, ActR-I antikoerper, ActRIA antikoerper, Acvr antikoerper, Acvrlk2 antikoerper, Alk-2 antikoerper, Alk8 antikoerper, D330013D15Rik antikoerper, Tsk7L antikoerper, actri antikoerper, acvr1 antikoerper, acvr1-a antikoerper, acvr1-b antikoerper, acvr1a antikoerper, acvrlk2 antikoerper, alk-2 antikoerper, alk2 antikoerper, alk8 antikoerper, fop antikoerper, sax antikoerper, skr1 antikoerper, tsri antikoerper, xALK-2 antikoerper, activin A receptor type 1 antikoerper, activin A receptor, type 1 antikoerper, activin A receptor type 1 S homeolog antikoerper, ACVR1 antikoerper, Acvr1 antikoerper, acvr1.S antikoerper

Hintergrund: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors.

UniProt: Q04771