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ACVR1 Produkte

(Activin Receptor Type I (ACRV1))
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008].

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Ausgewählte ACVR1 Kategorien

ACVR1 Antikörper

High quality antibodies with extensive validation data.

ACVR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

ACVR1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ACVR1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN392240
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN391156
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN657718
Menge 400 μL
Datenblatt Datenblatt

Empfohlene ACVR1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953435
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1745119
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1743901
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ACVR1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect cells (Sf21)
Validierungen
  • (2)
Kat. Nr. ABIN5569801
Menge 5 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect cells (Sf9)
Validierungen
  • (2)
Kat. Nr. ABIN5569800
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1305801
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ACVR1 Produkten

Tengroth, Arebro, Larsson, Bachert, Georén, Cardell: "Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps." in: Scientific reports, Vol. 8, Issue 1, pp. 1561, (2018) (PubMed).

Toofan, Busch, Morrison, OBrien, Jørgensen, Copland, Wheadon: "Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal." in: Cell death & disease, Vol. 9, Issue 9, pp. 927, (2018) (PubMed).

Fujimoto, Ohte, Shin, Yoneyama, Osawa, Miyamoto, Tsukamoto, Mizuta, Kokabu, Machiya, Okuda, Suda, Katagiri: "Establishment of a novel model of chondrogenesis using murine embryonic stem cells carrying fibrodysplasia ossificans progressiva-associated mutant ALK2." in: Biochemical and biophysical research communications, Vol. 455, Issue 3-4, pp. 347-52, (2014) (PubMed).

Kan, Liu, McGuire, Berger, Awatramani, Dymecki, Kessler: "Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 1, pp. 150-6, (2009) (PubMed).

Mitu, Wang, Hirschberg: "BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury." in: American journal of physiology. Renal physiology, Vol. 293, Issue 5, pp. F1641-8, (2007) (PubMed).

Shore, Xu, Feldman, Fenstermacher, Cho, Choi, Connor, Delai, Glaser, LeMerrer, Morhart, Rogers, Smith, Triffitt, Urtizberea, Zasloff, Brown, Kaplan: "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva." in: Nature genetics, Vol. 38, Issue 5, pp. 525-7, (2006) (PubMed).

Weber, Teresi, Broelsch, Frilling, Eng: "A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma." in: The Journal of clinical endocrinology and metabolism, Vol. 91, Issue 9, pp. 3584-91, (2006) (PubMed).

Masood, Kumar, Sinha, Crowe, Krasnoperov, Reddy, Zozulya, Singh, Xia, Broek, Schönthal, Gill: "EphB4 provides survival advantage to squamous cell carcinoma of the head and neck." in: International journal of cancer, Vol. 119, Issue 6, pp. 1236-48, (2006) (PubMed).

Casagrandi, Bearfield, Geary, Redman, Muttukrishna: "Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia." in: Molecular human reproduction, Vol. 9, Issue 4, pp. 199-203, (2003) (PubMed).

Schneider-Kolsky, Manuelpillai, Waldron, Dole, Wallace: "The distribution of activin and activin receptors in gestational tissues across human pregnancy and during labour." in: Placenta, Vol. 23, Issue 4, pp. 294-302, (2002) (PubMed).

Synonyme und alternative Namen zu ACVR1

activin A receptor type 1 (ACVR1), activin A receptor type 1 (Acvr1), activin A receptor, type 1 (Acvr1), activin A receptor type 1 S homeolog (acvr1.S), ActR-I, ActR-IA, ACTRI, actri, ActRIA, Acvr, acvr1, acvr1-a, acvr1-b, ACVR1A, acvr1a, ACVRLK2, Acvrlk2, acvrlk2, Alk-2, alk-2, ALK2, alk2, Alk8, alk8, D330013D15Rik, FOP, fop, sax, SKR1, skr1, Tsk7L, TSRI, tsri, xALK-2

Bezeichner auf Proteinebene für ACVR1

  • TGF-B superfamily receptor type I
  • activin A receptor, type II-like kinase 2
  • activin receptor type I
  • activin receptor type-1
  • activin receptor-like kinase 2
  • hydroxyalkyl-protein kinase
  • serine/threonine-protein kinase receptor R1
  • ACTR-I
  • SKR1
  • TSR-I
  • activin A receptor, type 1
  • activin type I receptor
  • type I TGF B receptor
  • activin A receptor, type I
  • activin receptor type IA
  • TSK-7L
  • activin A receptor type 1 S homeolog
  • activin A receptor type I S homeolog
  • activin receptor like kinase-2
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