TIRAP Antikörper (AA 1-221)
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- Target Alle TIRAP Antikörper anzeigen
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
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Bindungsspezifität
- AA 1-221
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TIRAP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- MASSTSLPAP GSRPKKPLGK MADWFRQTLL KKPKKRPNSP ESTSSDASQP TSQDSPLPPS LSSVTSPSLP PTHASDSGSS RWSKDYDVCV CHSEEDLVAA QDLVSYLEGS TASLRCFLQL RDATPGGAIV SELCQALSSS HCRVLLITPG FLQDPWCKYQ MLQALTEAPG AEGCTIPLLS GLSRAAYPPE LRFMYYVDGR GPDGGFRQVK EAVMRYLQTL S
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human TIRAP (NP_001034750.1).
- Isotyp
- IgG
- Top Product
- Discover our top product TIRAP Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes." in: Frontiers in molecular neuroscience, Vol. 10, pp. 409, (2017) (PubMed).
: "
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Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes." in: Frontiers in molecular neuroscience, Vol. 10, pp. 409, (2017) (PubMed).
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- Target
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
- Andere Bezeichnung
- TIRAP (TIRAP Produkte)
- Synonyme
- mal antikoerper, wyatt antikoerper, BACTS1 antikoerper, Mal antikoerper, MyD88-2 antikoerper, AA407980 antikoerper, C130027E04Rik antikoerper, Tlr4ap antikoerper, Wyatt antikoerper, toll-interleukin 1 receptor (TIR) domain containing adaptor protein antikoerper, TIR domain containing adaptor protein antikoerper, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog antikoerper, toll-interleukin 1 receptor (TIR) domain-containing adaptor protein antikoerper, tirap antikoerper, TIRAP antikoerper, tirap.L antikoerper, Tirap antikoerper
- Hintergrund
- The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.,TIRAP,BACTS1,Mal,MyD88-2,wyatt,Signal Transduction,Kinase,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,TIRAP
- Molekulargewicht
- 23 kDa/25 kDa/27 kDa
- Gen-ID
- 114609
- UniProt
- P58753
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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