Collagen Type I Antikörper

Produktnummer ABIN5959042

Produktdetails anti-Collagen Type I Antikörper

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Collagen Type I Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Alpha 2 collagen type I,Alpha 2 type I collagen,Alpha 2 type I procollagen,Alpha 2(I) collagen,Alpha 2(I) procollagen,Alpha-2 type I collagen,CO1A2,COL1A2,Collagen alpha 2(I) chain,Collagen alpha-2(I) chain,Collagen I alpha 2 polypeptide,Collagen of skin tendon and bone alpha 2 chain,Collagen type I alpha 2,OI4,Osteogenesis imperfecta type IV,Type I procollagen

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human Collagen I Polyclonal

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000, ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Collagen Type I

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Andere Bezeichnung: Collagen I (COL1 Produkte)

Synonyme: collagen type III alpha 1 chain antikoerper, COL3A1 antikoerper

Hintergrund: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. 

Gen-ID: 1278

UniProt: P08123