STAM Antikörper

Produktnummer ABIN5708332

Produktdetails anti-STAM Antikörper

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids F9-Q254 was used as the immunogen for the STAM1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the STAM1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the STAM1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu STAM

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Andere Bezeichnung: STAM1 (STAM Produkte)

Synonyme: STAM-1 antikoerper, STAM1 antikoerper, wu:fv75b10 antikoerper, zgc:55725 antikoerper, RGD1564499 antikoerper, signal transducing adaptor molecule antikoerper, signal transducing adapter molecule 1 antikoerper, Signal transducing adapter molecule 1 antikoerper, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 antikoerper, STAM antikoerper, CpipJ_CPIJ003516 antikoerper, Tsp_03939 antikoerper, stam-1 antikoerper, Stam antikoerper, stam antikoerper

Hintergrund: Signal transducing adapter molecule 1 is a protein that in humans is encoded by the STAM gene. This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.

UniProt: Q92783

Pathways: EGFR Signaling Pathway, EGFR Downregulation