Bestrophin 1 Antikörper

Produktnummer ABIN5708195

Produktdetails anti-Bestrophin 1 Antikörper

Target: Bestrophin 1 (BEST1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bestrophin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids RFIYRLALTEEQQLMFEKLTLYCD were used as the immunogen for the Bestrophin 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Bestrophin 1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Bestrophin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Bestrophin 1

Target: Bestrophin 1 (BEST1)

Andere Bezeichnung: Bestrophin 1 (BEST1 Produkte)

Synonyme: CG6264 antikoerper, Dbest antikoerper, Dmel\\CG6264 antikoerper, anon-WO0118547.380 antikoerper, best antikoerper, dBest1 antikoerper, dbest1 antikoerper, dmBest1 antikoerper, BEST1 antikoerper, VMD2 antikoerper, best-1 antikoerper, ARB antikoerper, BEST antikoerper, BMD antikoerper, RP50 antikoerper, TU15B antikoerper, Bmd antikoerper, Vmd2 antikoerper, mBest1 antikoerper, Bestrophin 1 antikoerper, bestrophin 1 antikoerper, Best1 antikoerper, BEST1 antikoerper, best1 antikoerper, Bm1_25500 antikoerper

Hintergrund: Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

UniProt: O76090