Notch1 Antikörper
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- Target Alle Notch1 (NOTCH1) Antikörper anzeigen
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Notch1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Immunogen
- Notch gene homolog 1 (Drosophila)
- Isotyp
- IgG
- Top Product
- Discover our top product NOTCH1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
- Andere Bezeichnung
- Notch1 (NOTCH1 Produkte)
- Synonyme
- notch1 antikoerper, NOTCH1 antikoerper, hn1 antikoerper, tan1 antikoerper, notch antikoerper, xotch antikoerper, xnotch antikoerper, notch-1 antikoerper, xnotch1 antikoerper, TAN1 antikoerper, hN1 antikoerper, 9930111A19Rik antikoerper, Mis6 antikoerper, N1 antikoerper, Tan1 antikoerper, lin-12 antikoerper, NOTCH antikoerper, Xotch antikoerper, notch1-a antikoerper, notch 1 antikoerper, fibropellin-1 antikoerper, Notch homolog 1, translocation-associated (Drosophila) antikoerper, Notch homolog 1, translocation-associated antikoerper, notch 1 S homeolog antikoerper, notch1 antikoerper, LOC100631526 antikoerper, NOTCH1 antikoerper, Notch1 antikoerper, notch1.S antikoerper
- Hintergrund
- Synonyms:AOS5, AOVD1, hN1, TAN1 Background:This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma.
- Molekulargewicht
- 270-300 kDa
- Gen-ID
- 4851
- UniProt
- P46531
- Pathways
- Notch Signalweg, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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