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Notch1 Antikörper (Cleaved-Val1754)

NOTCH1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7251301
  • Target Alle Notch1 (NOTCH1) Antikörper anzeigen
    Notch1 (NOTCH1) (Notch 1 (NOTCH1))
    Bindungsspezifität
    • 16
    • 16
    • 14
    • 11
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cleaved-Val1754
    Reaktivität
    • 117
    • 93
    • 48
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 93
    • 42
    • 6
    • 4
    • 3
    • 2
    • 1
    Kaninchen
    Klonalität
    • 88
    • 59
    • 2
    Polyklonal
    Konjugat
    • 69
    • 11
    • 9
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Notch1 Antikörper ist unkonjugiert
    Applikation
    • 95
    • 52
    • 51
    • 32
    • 27
    • 26
    • 23
    • 21
    • 15
    • 10
    • 10
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Synthesized peptide derived from the Internal region of human Notch 1
    Isotyp
    IgG
    Top Product
    Discover our top product NOTCH1 Primärantikörper
  • Applikationshinweise
    WB 1:500-2000, IHC 1:50-300, IF 1:50-300
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Notch1 (NOTCH1) (Notch 1 (NOTCH1))
    Andere Bezeichnung
    NOTCH1 (NOTCH1 Produkte)
    Synonyme
    notch1 antikoerper, NOTCH1 antikoerper, hn1 antikoerper, tan1 antikoerper, notch antikoerper, xotch antikoerper, xnotch antikoerper, notch-1 antikoerper, xnotch1 antikoerper, TAN1 antikoerper, hN1 antikoerper, 9930111A19Rik antikoerper, Mis6 antikoerper, N1 antikoerper, Tan1 antikoerper, lin-12 antikoerper, NOTCH antikoerper, Xotch antikoerper, notch1-a antikoerper, notch 1 antikoerper, fibropellin-1 antikoerper, Notch homolog 1, translocation-associated (Drosophila) antikoerper, Notch homolog 1, translocation-associated antikoerper, notch 1 S homeolog antikoerper, notch1 antikoerper, LOC100631526 antikoerper, NOTCH1 antikoerper, Notch1 antikoerper, notch1.S antikoerper
    Hintergrund
    This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.
    Molekulargewicht

    Observed_MW: 110 kDa

    Calculated_MW: 273 kDa

    UniProt
    P46531
    Pathways
    Notch Signalweg, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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