ATG4C Antikörper

Produktnummer ABIN5702082

Produktdetails anti-ATG4C Antikörper

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG4C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: ATG4 autophagy related 4 homolog C (S. cerevisiae)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab00675(ATG4C antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu ATG4C

Target: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Andere Bezeichnung: ATG4C (ATG4C Produkte)

Synonyme: apg4c antikoerper, atg4cl antikoerper, zgc:86888 antikoerper, wu:fc56g07 antikoerper, APG4-C antikoerper, APG4C antikoerper, AUTL1 antikoerper, AUTL3 antikoerper, Apg4-C antikoerper, Apg4c antikoerper, Atg4cl antikoerper, Autl1 antikoerper, autophagy related 4C cysteine peptidase antikoerper, autophagy related 4C, cysteine peptidase antikoerper, cysteine protease ATG4C antikoerper, ATG4C antikoerper, atg4c antikoerper, Tsp_15996 antikoerper, Atg4c antikoerper

Hintergrund: Synonyms:APG4C, AUTL1, AUTL3 Background:Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation(By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Molekulargewicht: 52-55 kDa

Gen-ID: 84938

UniProt: Q96DT6

Pathways: Autophagie