USP44 Antikörper
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- Target Alle USP44 Antikörper anzeigen
- USP44 (Ubiquitin Specific Peptidase 44 (USP44))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser USP44 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Immunogen
- ubiquitin specific peptidase 44
- Isotyp
- IgG
- Top Product
- Discover our top product USP44 Primärantikörper
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- Applikationshinweise
- WB : 1:500-1:5000
- Kommentare
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human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09334(USP44 antibody) at dilution of 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- USP44 (Ubiquitin Specific Peptidase 44 (USP44))
- Andere Bezeichnung
- USP44 (USP44 Produkte)
- Synonyme
- usp44 antikoerper, USP49 antikoerper, E430004F17Rik antikoerper, zgc:55661 antikoerper, ubiquitin specific peptidase 44 antikoerper, ubiquitin specific peptidase 44 L homeolog antikoerper, ubiquitin specific peptidase 44 S homeolog antikoerper, USP44 antikoerper, usp44.L antikoerper, usp44.S antikoerper, usp44 antikoerper, Usp44 antikoerper
- Hintergrund
- Synonyms:Deubiquitinating enzyme 44, DKFZp434D0127, FLJ14528, Ubiquitin thiolesterase 44, USP44 Background:Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome(APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex(also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B(H2BK120ub1) ubiquitination.
- Molekulargewicht
- 145kDa
- Gen-ID
- 84101
- UniProt
- Q9H0E7
- Pathways
- M Phase
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