COPS3 Antikörper
-
- Target Alle COPS3 Antikörper anzeigen
- COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser COPS3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogen
- COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)
- Isotyp
- IgG
- Top Product
- Discover our top product COPS3 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
-
human brain tissue were subjected to SDS PAGE followed by western blot with FNab01871(COPS3 antibody) at dilution of 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
-
- Target
- COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
- Andere Bezeichnung
- COPS3 (COPS3 Produkte)
- Synonyme
- CG18332 antikoerper, CH3 antikoerper, Csn3 antikoerper, DCH3 antikoerper, Dch3 antikoerper, Dmel\\CG18332 antikoerper, FBgn0027055 antikoerper, dCSN3 antikoerper, COPS3 antikoerper, CSN3 antikoerper, DKFZp468P1922 antikoerper, Sgn3 antikoerper, wu:fc32a02 antikoerper, wu:fk59f01 antikoerper, zgc:111903 antikoerper, zgc:55643 antikoerper, zgc:77615 antikoerper, CONSTITUTIVE PHOTOMORPHOGENIC 13 antikoerper, COP9 SIGNALOSOME SUBUNIT 3 antikoerper, F18O22.40 antikoerper, F18O22_40 antikoerper, FUS11 antikoerper, FUSCA 11 antikoerper, SGN3 antikoerper, csn3 antikoerper, COP9 signalosome subunit 3 antikoerper, Proteasome component (PCI) domain protein antikoerper, COP9 signalosome subunit 3 L homeolog antikoerper, COP9 signalosome complex subunit 3 antikoerper, CSN3 antikoerper, cops3 antikoerper, COPS3 antikoerper, Cops3 antikoerper, COP13 antikoerper, cops3.L antikoerper, csn-3 antikoerper
- Hintergrund
- Synonyms:CSN3 Background:Component of the COP9 signalosome complex(CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin(Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- Molekulargewicht
- 48 kDa
- Gen-ID
- 8533
- UniProt
- Q9UNS2
- Pathways
- Zellzyklus
-