DPP4 Antikörper

Produktnummer ABIN5700468

Produktdetails anti-DPP4 Antikörper

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reaktivität: Human, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Immunogen: dipeptidyl-peptidase 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

PC-3 cells were subjected to SDS PAGE followed by western blot with FNab02520(DPP4 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Andere Bezeichnung: DPP4 (DPP4 Produkte)

Synonyme: ADABP antikoerper, ADCP2 antikoerper, CD26 antikoerper, DPPIV antikoerper, TP103 antikoerper, MGC81966 antikoerper, MOP9.8 antikoerper, MOP9_8 antikoerper, DPP4 antikoerper, si:ch73-2d23.3 antikoerper, Cd26 antikoerper, Dpp-4 antikoerper, THAM antikoerper, dipeptidyl peptidase 4 antikoerper, dipeptidyl-peptidase 4 S homeolog antikoerper, prolyl oligopeptidase family protein antikoerper, dipeptidyl-peptidase 4 antikoerper, dipeptidylpeptidase 4 antikoerper, DPP4 antikoerper, dpp4.S antikoerper, AT5G24260 antikoerper, dpp4 antikoerper, Dpp4 antikoerper

Hintergrund: Synonyms:ADABP, ADCP 2, ADCP2, CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DPP4, DPPIV, T cell activation antigen CD26, TP103 Background:Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix(ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

Molekulargewicht: 55-60 kDa

Gen-ID: 1803

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity