DPP4 Antikörper (Dipeptidyl-Peptidase 4) (PE)

Produktnummer ABIN1303125

Produktdetails anti-DPP4 Antikörper

Target: DPP4

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DPP4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: The mouse monoclonal antibody BA5b recognizes CD26, a 110 kDa type II membrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.
HLDA VI, WS Code N-L078

Kreuzreaktivität (Details): Human

Immunogen: A human T cell clone

Klon: BA5b

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (2 ml) is sufficient for 100 tests.

Kommentare:

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: No reconstitution is necessary.

Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.
Avoid prolonged exposure to light.

Lagerung: 4 °C

Informationen zur Lagerung: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.

Details zu DPP4

Target: DPP4

Andere Bezeichnung: CD26 (DPP4 Produkte)

Synonyme: ADABP, ADCP2, CD26, DPPIV, TP103, MGC81966, MOP9.8, MOP9_8, DPP4, si:ch73-2d23.3, Cd26, Dpp-4, THAM, dipeptidyl peptidase 4, dipeptidyl-peptidase 4 S homeolog, prolyl oligopeptidase family protein, dipeptidyl-peptidase 4, dipeptidylpeptidase 4, DPP4, dpp4.S, AT5G24260, dpp4, Dpp4

Hintergrund: CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity