ROCK2 Antikörper
-
- Target Alle ROCK2 Antikörper anzeigen
- ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ROCK2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- Immunogen
- Rho-associated, coiled-coil containing protein kinase 2
- Isotyp
- IgG
- Top Product
- Discover our top product ROCK2 Primärantikörper
-
-
- Applikationshinweise
- WB:1:1000-1:10000 IP:1:200-1:2000 IHC:1:20-1:200 IF:1:10-1:100
- Kommentare
-
HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab07378(ROCK2 antibody) at dilution of 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
-
- Target
- ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
- Andere Bezeichnung
- ROCK2 (ROCK2 Produkte)
- Synonyme
- rocka-a antikoerper, xROK antikoerper, rock2 antikoerper, rok2 antikoerper, ROCK2 antikoerper, B230113H15Rik antikoerper, ROKalpha antikoerper, Rho-kinase antikoerper, Rock-II antikoerper, Rock2m antikoerper, mKIAA0619 antikoerper, ROCK-II antikoerper, ROK antikoerper, Rho-associated, coiled-coil containing protein kinase 2 L homeolog antikoerper, rho-associated, coiled-coil containing protein kinase 2a antikoerper, Rho associated coiled-coil containing protein kinase 2 antikoerper, Rho-associated, coiled-coil containing protein kinase 2 antikoerper, Rho-associated coiled-coil containing protein kinase 2 antikoerper, rock2.L antikoerper, rock2a antikoerper, ROCK2 antikoerper, Rock2 antikoerper
- Hintergrund
- Synonyms:KIAA0619 Background:Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.
- Gen-ID
- 9475
- UniProt
- O75116
- Pathways
- Microtubule Dynamics, WNT Signalweg, Tube Formation
-