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ROCK2 Antikörper

KO Validated ROCK2 Reaktivität: Human WB, IP, IF, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855440
  • Target Alle ROCK2 Antikörper anzeigen
    ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
    Reaktivität
    • 105
    • 69
    • 69
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 97
    • 9
    • 1
    Kaninchen
    Klonalität
    • 95
    • 12
    Polyklonal
    Konjugat
    • 48
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ROCK2 Antikörper ist unkonjugiert
    Applikation
    • 75
    • 36
    • 27
    • 27
    • 19
    • 18
    • 16
    • 12
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to ROCK2 (Rho-associated, coiled-coil containing protein kinase 2)
    ROCK2 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human ROCK2. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product ROCK2 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: Rat2 , Neuro 2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , A549 , H1299 , HCT116 , 293T , A431 , HeLa , HepG2

    Validation: Comparison, KO/KD, Orthogonal

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.67 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
    Andere Bezeichnung
    Rho associated coiled-coil containing protein kinase 2 (ROCK2 Produkte)
    Hintergrund
    The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.

    Cellular Localization: Cytoplasm (By similarity) , Cell membrane, Peripheral membrane protein (By similarity)
    Molekulargewicht
    161 kDa
    Gen-ID
    9475
    UniProt
    O75116
    Pathways
    Microtubule Dynamics, WNT Signalweg, Tube Formation
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