DKK1 Antikörper

Produktnummer ABIN5698859

Produktdetails anti-DKK1 Antikörper

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DKK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: dickkopf homolog 1 (Xenopus laevis)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

human placenta tissue were subjected to SDS PAGE followed by western blot with FNab02401(DKK1 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Andere Bezeichnung: DKK1 (DKK1 Produkte)

Synonyme: DKK-1 antikoerper, SK antikoerper, AI414495 antikoerper, SGY antikoerper, SGY-1 antikoerper, SGY1 antikoerper, Soggy antikoerper, mSgy antikoerper, dkk1 antikoerper, dkk antikoerper, dkk-1 antikoerper, xdkk1 antikoerper, Xdkk-1 antikoerper, Dickkopf1 antikoerper, dickkopf-1 antikoerper, mdkk-1 antikoerper, dkk1-A antikoerper, dickkopf WNT signaling pathway inhibitor 1 antikoerper, dickkopf like acrosomal protein 1 antikoerper, dickkopf-related protein 1 antikoerper, dickkopf-like 1 antikoerper, dickkopf WNT signaling pathway inhibitor 1b antikoerper, dickkopf protein antikoerper, dickkopf WNT signaling pathway inhibitor 1 S homeolog antikoerper, DKK1 antikoerper, Dkk1 antikoerper, DKKL1 antikoerper, LOC100228789 antikoerper, Dkkl1 antikoerper, dkk1b antikoerper, dkk1 antikoerper, dickkopf antikoerper, dkk1.S antikoerper

Hintergrund: Synonyms:Dickkopf 1, Dickkopf related protein 1, DKK 1, DKK1, hDkk 1, SK Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Molekulargewicht: 30-35 kDa

Gen-ID: 22943

UniProt: O94907

Pathways: WNT Signalweg, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation