TWEAK Antikörper (AA 94-249)
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- Target Alle TWEAK (TNFSF12) Antikörper anzeigen
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
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Bindungsspezifität
- AA 94-249
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TWEAK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Marke
- Picoband™
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
- Rabbit IgG polyclonal antibody for TWEAK detection. Tested with WB, ELISA(Cap) in Human,Mouse,Rat.
- Immunogen
- E. coli-derived human TWEAK recombinant protein (Position: S94-H249).
- Top Product
- Discover our top product TNFSF12 Primärantikörper
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- Applikationshinweise
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
ELISA(Cap), 1-5 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- Target
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- Andere Bezeichnung
- TNFSF12 (TNFSF12 Produkte)
- Synonyme
- APO3L antikoerper, DR3LG antikoerper, TWEAK antikoerper, Apo3l antikoerper, Dr3l antikoerper, Dr3lg antikoerper, Tweak antikoerper, TNF superfamily member 12 antikoerper, tumor necrosis factor (ligand) superfamily, member 12 antikoerper, TNFSF12 antikoerper, Tnfsf12 antikoerper
- Hintergrund
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Synonyms: Tumor necrosis factor ligand superfamily member 12, APO3 ligand, TNF-related weak inducer of apoptosis, TWEAK, Tumor necrosis factor ligand superfamily member 12, membrane form, Tumor necrosis factor ligand superfamily member 12, secreted form, TNFSF12, APO3L, DR3LG, UNQ181/PRO207
Tissue Specificity: Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain.
Background: Tumor necrosis factor ligand superfamily member 12 also known as TNF-related weak inducer of apoptosis (TWEAK) is a protein that in humans is encoded by the TNFSF12 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants.
- UniProt
- O43508
- Pathways
- Apoptose
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