EPS15 Antikörper (AA 2-88)

Produktnummer ABIN5693046

Produktdetails anti-EPS15 Antikörper

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Bindungsspezifität: AA 2-88

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPS15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for EPS15 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human EPS15 recombinant protein (Position: A2-E88).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu EPS15

Target: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Andere Bezeichnung: EPS15 (EPS15 Produkte)

Synonyme: AF-1P antikoerper, AF1P antikoerper, MLLT5 antikoerper, CG16932 antikoerper, Dmel\\CG16932 antikoerper, EH1 antikoerper, EPS-15 antikoerper, Eps15 antikoerper, anon-WO0118547.85 antikoerper, eps-15 antikoerper, eps15 antikoerper, i31 antikoerper, 2410112D09Rik antikoerper, RGD1307641 antikoerper, epidermal growth factor receptor pathway substrate 15 antikoerper, Epidermal growth factor receptor pathway substrate clone 15 antikoerper, hypothetical protein antikoerper, EPS15 antikoerper, Eps-15 antikoerper, eps15 antikoerper, Eps15 antikoerper, PGTG_06574 antikoerper

Hintergrund:

Synonyms: Epidermal growth factor receptor substrate 15, Protein Eps15, Protein AF-1p, EPS15, AF1P

Tissue Specificity: Ubiquitously expressed.

Background: Epidermal growth factor receptor substrate 15 is a protein that in humans is encoded by the EPS15 gene. This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

UniProt: P42566

Pathways: EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation