STAM Antikörper (AA 9-254)

Produktnummer ABIN5693019

Produktdetails anti-STAM Antikörper

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Bindungsspezifität: AA 9-254

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for STAM1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human STAM1 recombinant protein (Position: F9-Q254).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu STAM

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Andere Bezeichnung: STAM (STAM Produkte)

Synonyme: STAM-1 antikoerper, STAM1 antikoerper, wu:fv75b10 antikoerper, zgc:55725 antikoerper, RGD1564499 antikoerper, signal transducing adaptor molecule antikoerper, signal transducing adapter molecule 1 antikoerper, Signal transducing adapter molecule 1 antikoerper, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 antikoerper, STAM antikoerper, CpipJ_CPIJ003516 antikoerper, Tsp_03939 antikoerper, stam-1 antikoerper, Stam antikoerper, stam antikoerper

Hintergrund:

Synonyms: Signal transducing adapter molecule 1, STAM-1, STAM, STAM1

Tissue Specificity: Ubiquitously expressed.

Background: Signal transducing adapter molecule 1 is a protein that in humans is encoded by the STAM gene. This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.

UniProt: Q92783

Pathways: EGFR Signaling Pathway, EGFR Downregulation