GLIS2 Antikörper (AA 260-310)

Produktnummer ABIN5689976

Produktdetails anti-GLIS2 Antikörper

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Bindungsspezifität: AA 260-310

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLIS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: GLIS2 antibody is human, mouse and rat reactive.

Aufreinigung: GLIS2 antibody is affinity chromatography purified via peptide column.

Immunogen: GLIS2 antibody was raised against an 18 amino acid peptide near the center of human GLIS2.

The immunogen is located within amino acids 260 - 310 of GLIS2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GLIS2 antibody can be used for detection of GLIS2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GLIS2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: GLIS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu GLIS2

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Andere Bezeichnung: GLIS2 (GLIS2 Produkte)

Synonyme: glis2b antikoerper, nkl-A antikoerper, xNKLb antikoerper, NKL antikoerper, NPHP7 antikoerper, Gli5 antikoerper, Klf16 antikoerper, Nkl antikoerper, glis2a antikoerper, nphp7 antikoerper, GLIS family zinc finger 2 L homeolog antikoerper, GLIS family zinc finger 2 antikoerper, GLIS family zinc finger 2 S homeolog antikoerper, glis2.L antikoerper, GLIS2 antikoerper, Glis2 antikoerper, glis2.S antikoerper

Hintergrund: GLIS2, also known as neuronal Krueppel-like, is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family (1). GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation (1,2). GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta. Mutations of GLIS2 have been suggested to be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis (3,4).

Molekulargewicht: Predicted: 58 kDa

Observed: 60 kDa

Gen-ID: 84662

NCBI Accession: NP_115964

UniProt: Q9BZE0