GLIS2 Antikörper (AA 332-505) (Biotin)

Produktnummer ABIN7176583

Produktdetails anti-GLIS2 Antikörper (Biotin)

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Bindungsspezifität: AA 332-505

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLIS2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Zinc finger protein GLIS2 protein (332-505AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GLIS2

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Andere Bezeichnung: GLIS2 (GLIS2 Produkte)

Synonyme: glis2b antikoerper, nkl-A antikoerper, xNKLb antikoerper, NKL antikoerper, NPHP7 antikoerper, Gli5 antikoerper, Klf16 antikoerper, Nkl antikoerper, glis2a antikoerper, nphp7 antikoerper, GLIS family zinc finger 2 L homeolog antikoerper, GLIS family zinc finger 2 antikoerper, GLIS family zinc finger 2 S homeolog antikoerper, glis2.L antikoerper, GLIS2 antikoerper, Glis2 antikoerper, glis2.S antikoerper

Hintergrund:

Background: Can act either as a transcriptional repressor or as a transcriptional activator, depending on the cell context. Acts as a repressor of the Hedgehog signaling pathway (By similarity). Represses the Hedgehog-dependent expression of Wnt4 (By similarity). Necessary to maintain the differentiated epithelial phenotype in renal cells through the inhibition of SNAI1, which itself induces the epithelial-to-mesenchymal transition (By similarity). Represses transcriptional activation mediated by CTNNB1 in the Wnt signaling pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation (By similarity).

Aliases: FLJ38247 antibody, GLI similar 2 antibody, GLI-similar 2 antibody, GLIS 2 antibody, GLIS family zinc finger 2 antibody, glis2 antibody, GLIS2_HUMAN antibody, Kruppel like zinc finger protein GLIS2 antibody, Neuronal Krueppel-like protein antibody, Zinc finger protein GLIS2 antibody

UniProt: Q9BZE0