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GLIS2 Antikörper (AA 271-350) (Biotin)

GLIS2 Reaktivität: Ratte, Maus WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1392031
  • Target Alle GLIS2 Antikörper anzeigen
    GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
    Bindungsspezifität
    • 14
    • 7
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 271-350
    Reaktivität
    • 24
    • 18
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Ratte, Maus
    Wirt
    • 38
    Kaninchen
    Klonalität
    • 38
    Polyklonal
    Konjugat
    • 12
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GLIS2 Antikörper ist konjugiert mit Biotin
    Applikation
    • 34
    • 19
    • 13
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GLIS2
    Isotyp
    IgG
    Top Product
    Discover our top product GLIS2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
    Andere Bezeichnung
    GLIS2 (GLIS2 Produkte)
    Synonyme
    glis2b antikoerper, nkl-A antikoerper, xNKLb antikoerper, NKL antikoerper, NPHP7 antikoerper, Gli5 antikoerper, Klf16 antikoerper, Nkl antikoerper, glis2a antikoerper, nphp7 antikoerper, GLIS family zinc finger 2 L homeolog antikoerper, GLIS family zinc finger 2 antikoerper, GLIS family zinc finger 2 S homeolog antikoerper, glis2.L antikoerper, GLIS2 antikoerper, Glis2 antikoerper, glis2.S antikoerper
    Hintergrund

    Synonyms: NPHP7, NKL, GLI kruppel family member 2, GLI similar 2, GLI-similar 2, GLIS 2, GLIS family zinc finger 2, glis2, GLIS2_HUMAN, Kruppel like zinc finger protein GLIS2, Neuronal Krueppel-like protein, Tax helper protein, THP, Zinc finger protein GLI2, Zinc finger protein GLIS2.

    Background: GLIS2 is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family. By recruiting the corepressors CtBP1 and HDAC3, GLIS2 represses the transcriptional activation mediated by a??-catenin in the Wnt pathway. GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation. Mutations of GLIS2 may be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis. GLIS2 contains five tandem Cys(2)-His(2) zinc finger motifs that exhibit the highest homology to those of members of the GLI and Zic subfamilies of Kr??ppel-like proteins. GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta.

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