POT1 Antikörper (AA 497-634)

Produktnummer ABIN6218570

Produktdetails anti-POT1 Antikörper

Target: POT1 (Protection of Telomeres 1 (POT1))

Bindungsspezifität: AA 497-634

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TIHHYGCKQC SSLRSIQNLN SLVDKTSWIP SSVAEALGIV PLQYVFVMTF TLDDGTGVLE AYLMDSDKFF QIPASEVLMD DDLQKSVDMI MDMFCPPGIK IDAYPWLECF IKSYNVTNGT DNQICYQIFD TTVAEDVI

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1 (NP_056265.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu POT1

Target: POT1 (Protection of Telomeres 1 (POT1))

Andere Bezeichnung: POT1 (POT1 Produkte)

Synonyme: HPOT1 antikoerper, POT1 antikoerper, DKFZp469P1825 antikoerper, pot1 antikoerper, 1500031H18Rik antikoerper, AI851169 antikoerper, Pot1 antikoerper, Pot1a antikoerper, protection of telomeres 1 antikoerper, protection of telomeres 1 L homeolog antikoerper, protection of telomeres 1A antikoerper, POT1 antikoerper, pot1.L antikoerper, Pot1a antikoerper, Pot1 antikoerper

Hintergrund: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.,POT1,CMM10,GLM9,HPOT1,Epigenetics & Nuclear Signaling,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,POT1

Molekulargewicht: 60 kDa/71 kDa

Gen-ID: 25913

UniProt: Q9NUX5

Pathways: Zellzyklus, Telomere Maintenance