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POT1 Antikörper (Middle Region)

POT1 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Hund, Rind (Kuh), Schwein, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2787632
  • Target Alle POT1 Antikörper anzeigen
    POT1 (Protection of Telomeres 1 (POT1))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Meerschweinchen, Pferd, Hund, Rind (Kuh), Schwein, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 21
    • 1
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POT1 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 9
    • 2
    • 2
    Western Blotting (WB)
    Sequenz
    MNSENQTMLS LEFHLHGGTS YGRGIRVLPE SNSDVDQLKK DLESANLTAN
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against POT1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human POT1
    Top Product
    Discover our top product POT1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 634 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    POT1 (Protection of Telomeres 1 (POT1))
    Andere Bezeichnung
    POT1 (POT1 Produkte)
    Synonyme
    HPOT1 antikoerper, POT1 antikoerper, DKFZp469P1825 antikoerper, pot1 antikoerper, 1500031H18Rik antikoerper, AI851169 antikoerper, Pot1 antikoerper, Pot1a antikoerper, protection of telomeres 1 antikoerper, protection of telomeres 1 L homeolog antikoerper, protection of telomeres 1A antikoerper, POT1 antikoerper, pot1.L antikoerper, Pot1a antikoerper, Pot1 antikoerper
    Hintergrund
    This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
    Alias Symbols: DKFZP586D211, hPot1, HPOT1
    Protein Interaction Partner: TPP1, CFL2, ACD, CORO1A, KHDRBS1, LAMC3, BCAS2, MVP, ZNF32, ECI1, CSNK2B, COX6A2, ALDH1A1, ACTN4, SERTAD1, C2orf74, ZBTB49, ZBED2, CYP4F11, MYO5C, RIF1, NAP1L1, MDM2, KRT18, GRN, PACSIN1, SULT4A1, PGLS, AIPL1, SH3BP1, HAAO, NCDN, TWF2, ACOT7, DDX19B, PACS
    Protein Size: 634
    Molekulargewicht
    70 kDa
    Gen-ID
    25913
    NCBI Accession
    NM_015450, NP_056265
    UniProt
    Q9NUX5
    Pathways
    Zellzyklus, Telomere Maintenance
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