Arrestin 3 Antikörper (Internal Region)
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- Target Alle Arrestin 3 (ARRB2) Antikörper anzeigen
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser Arrestin 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Sequenz
- C-HDHIPLPRPQ S
- Spezifität
- This antibody is expected to recognizse both reported isoforms NP_004304.1 and NP_945355.1. No cross-reactivity is expected with Arrestin beta 1.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse, Rat.
- Aufreinigung
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
- Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_004304.1, NP_945355.1. Genename: ARRB2
- Top Product
- Discover our top product ARRB2 Primärantikörper
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- Applikationshinweise
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Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Urinary biomarkers of chronic allograft nephropathy." in: Proteomics. Clinical applications, Vol. 9, Issue 5-6, pp. 574-85, (2015) (PubMed).
: "Generation of induced pluripotent stem cells from human renal proximal tubular cells with only two transcription factors, OCT4 and SOX2." in: The Journal of biological chemistry, Vol. 287, Issue 29, pp. 24131-8, (2012) (PubMed).
: "Reduced expression of arrestin beta 2 by graft monocytes during acute rejection of rat kidneys." in: Immunobiology, Vol. 216, Issue 7, pp. 854-61, (2011) (PubMed).
: "
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Urinary biomarkers of chronic allograft nephropathy." in: Proteomics. Clinical applications, Vol. 9, Issue 5-6, pp. 574-85, (2015) (PubMed).
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- Target
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
- Andere Bezeichnung
- Arrestin beta-2 / ARRB2 (ARRB2 Produkte)
- Synonyme
- ARRB2 antikoerper, arb2 antikoerper, arr2 antikoerper, arrestin antikoerper, barr2 antikoerper, betaarr2 antikoerper, ARB2 antikoerper, ARR2 antikoerper, BARR2 antikoerper, BARRES antikoerper, AI326910 antikoerper, AW122872 antikoerper, arrb2 antikoerper, zgc:64007 antikoerper, arrestin beta 2 antikoerper, arrestin, beta 2 antikoerper, arrestin beta 2 L homeolog antikoerper, arrestin, beta 2b antikoerper, ARRB2 antikoerper, arrb2 antikoerper, Arrb2 antikoerper, arrb2.L antikoerper, arrb2b antikoerper
- Hintergrund
- Members of arrestin/beta arrestin protein family are thought to participate in agonist mediated desensitization of G protein coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors.Synonyms: ARB2, ARR2, Beta-arrestin-2
- Molekulargewicht
- 46.1 kDa according to NP_004304.1 and 44.4 according to NP_945355.1.
- Gen-ID
- 409, 9606
- UniProt
- P32121
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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