KDM4C Antikörper (C-Term)

Produktnummer ABIN5536323

Produktdetails anti-KDM4C Antikörper

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Bindungsspezifität: AA 1023-1056, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM4C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This JMJD2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1023-1056 amino acids from the C-terminal region of human JMJD2C.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For FACS starting dilution is: 1:25

For WB starting dilution is: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.41 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu KDM4C

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Andere Bezeichnung: JMJD2C (KDM4C Produkte)

Synonyme: JMJD2C antikoerper, GASC1 antikoerper, JHDM3C antikoerper, TDRD14C antikoerper, bA146B14.1 antikoerper, 2410141F18Rik antikoerper, AA517467 antikoerper, Gasc1 antikoerper, Jmjd2c antikoerper, lysine demethylase 4C antikoerper, jumonji domain containing 2c antikoerper, lysine (K)-specific demethylase 4C antikoerper, KDM4C antikoerper, Jmjd2c antikoerper, kdm4c antikoerper, Kdm4c antikoerper

Hintergrund: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 120 kDa

Gen-ID: 23081

UniProt: Q9H3R0

Pathways: Nuclear Hormone Receptor Binding, Warburg Effekt