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KDM4C Produkte

(Lysine (K)-Specific Demethylase 4C (KDM4C))

Kategorien

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

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Ausgewählte KDM4C Kategorien

KDM4C Antikörper

High quality antibodies with extensive validation data.

KDM4C Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene KDM4C Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, FACS
Validierungen
  • (3)
Kat. Nr. ABIN655391
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Bat, Cow, Dog, Horse, Human, Monkey, Mouse, Rabbit, Rat
Applikation WB, IHC, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN6744419
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7158700
Menge 100 μg
Datenblatt Datenblatt

Empfohlene KDM4C Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3136699
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3093322
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Baculovirus
Validierungen
  • (2)
Kat. Nr. ABIN2669706
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren KDM4C Produkten

Kalainayakan, Ghosh, Dey, Fitzgerald, Sohoni, Konduri, Garrossian, Liu, Zhang: "Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression." in: Scientific reports, Vol. 9, Issue 1, pp. 1405, (2019) (PubMed).

Wu, Cheng, Yeh, Li, Chen, Sit, Chuu, Kung, Chien, Wang: "KDM4B is a coactivator of c-Jun and involved in gastric carcinogenesis." in: Cell death & disease, Vol. 10, Issue 2, pp. 68, (2019) (PubMed).

Xu, Moresco, Chang, Mukim, Smith, Diedrich, Yates, Jones: "SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007071, (2018) (PubMed).

Qiu, Fan, Zhu, Kwan, Chen, Chen, Ying, Zhou, Gu, Wang, Cheng, Zeng, Wan, Mok, Wong, Bao: "KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1." in: Oncotarget, Vol. 6, Issue 31, pp. 31702-20, (2015) (PubMed).

Ratovitski: "Phospho-ΔNp63α/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomas." in: Cell cycle (Georgetown, Tex.), Vol. 13, Issue 5, pp. 749-61, (2014) (PubMed).

Walsh, Bolger, Byrne, Cocchiglia, Hao, Fagan, Qin, Cahalin, McCartan, McIlroy, OGaora, Xu, Hill, Young: "Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis." in: Cancer research, Vol. 74, Issue 9, pp. 2533-44, (2014) (PubMed).

Lee, Yang, Park: "Hypoxia enhances the expression of prostate-specific antigen by modifying the quantity and catalytic activity of Jumonji C domain-containing histone demethylases." in: Carcinogenesis, Vol. 34, Issue 12, pp. 2706-15, (2013) (PubMed).

Young, McDonald, Hendzel: "Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation." in: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 21376-88, (2013) (PubMed).

Lu, Ward, Kapoor, Rohle, Turcan, Abdel-Wahab, Edwards, Khanin, Figueroa, Melnick, Wellen, ORourke, Berger, Chan, Levine, Mellinghoff, Thompson: "IDH mutation impairs histone demethylation and results in a block to cell differentiation." in: Nature, Vol. 483, Issue 7390, pp. 474-8, (2012) (PubMed).

Mallette, Mattiroli, Cui, Young, Hendzel, Mer, Sixma, Richard: "RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites." in: The EMBO journal, Vol. 31, Issue 8, pp. 1865-78, (2012) (PubMed).

Synonyme und alternative Namen zu KDM4C

lysine demethylase 4C (KDM4C), jumonji domain containing 2c (Jmjd2c), lysine demethylase 4C (kdm4c), lysine (K)-specific demethylase 4C (Kdm4c), lysine demethylase 4C (Kdm4c), 2410141F18Rik, AA517467, bA146B14.1, GASC1, Gasc1, JHDM3C, JMJD2C, Jmjd2c, TDRD14C

Bezeichner auf Proteinebene für KDM4C

  • jumonji domain containing 2C
  • lysine (K)-specific demethylase 4C
  • jumonji domain containing 2c
  • lysine-specific demethylase 4C
  • lysine-specific demethylase 4C-like
  • GASC-1 protein
  • JmjC domain-containing histone demethylation protein 3C
  • gene amplified in squamous cell carcinoma 1 protein
  • jumonji domain-containing protein 2C
  • tudor domain containing 14C
  • gene amplified in squamous cell carcinoma 1
  • jmjC domain-containing histone demethylation protein 3C
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