GFR Antikörper (C-Term)

Produktnummer ABIN5535165

Produktdetails anti-GFR Antikörper

Target: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Bindungsspezifität: AA 529-555, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAPGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 529-555 amino acids from the C-terminal region of human RAPGEF5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GFR

Target: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Andere Bezeichnung: RAPGEF5 (RAPGEF5 Produkte)

Synonyme: GFR antikoerper, MR-GEF antikoerper, REPAC antikoerper, 4932413M22 antikoerper, C86120 antikoerper, D030051B22Rik antikoerper, Mrgef antikoerper, mKIAA0277 antikoerper, mmr-gef antikoerper, RGD1562891 antikoerper, rMR-GEF antikoerper, MGC154311 antikoerper, Rap guanine nucleotide exchange factor 5 antikoerper, Rap guanine nucleotide exchange factor (GEF) 5 antikoerper, Rap guanine nucleotide exchange factor 5 S homeolog antikoerper, RAPGEF5 antikoerper, Rapgef5 antikoerper, rapgef5.S antikoerper

Hintergrund: Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).

Molekulargewicht: 68 kDa

Gen-ID: 9771

UniProt: Q92565

Pathways: RTK Signalweg, Neurotrophin Signalübertragung, Hepatitis C