GFR Antikörper (C-Term)

Produktnummer ABIN1537440

Produktdetails anti-GFR Antikörper

Target: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Bindungsspezifität: AA 529-555, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAPGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 529-555 amino acids from the C-terminal region of human RAPGEF5.

Klon: RB36938

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: RAPGEF5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu GFR

Target: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Andere Bezeichnung: RAPGEF5 (RAPGEF5 Produkte)

Synonyme: GFR antikoerper, MR-GEF antikoerper, REPAC antikoerper, 4932413M22 antikoerper, C86120 antikoerper, D030051B22Rik antikoerper, Mrgef antikoerper, mKIAA0277 antikoerper, mmr-gef antikoerper, RGD1562891 antikoerper, rMR-GEF antikoerper, MGC154311 antikoerper, Rap guanine nucleotide exchange factor 5 antikoerper, Rap guanine nucleotide exchange factor (GEF) 5 antikoerper, Rap guanine nucleotide exchange factor 5 S homeolog antikoerper, RAPGEF5 antikoerper, Rapgef5 antikoerper, rapgef5.S antikoerper

Hintergrund: Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).

Molekulargewicht: 67733

Gen-ID: 9771

NCBI Accession: NP_036426

UniProt: Q92565

Pathways: RTK Signalweg, Neurotrophin Signalübertragung, Hepatitis C