This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SERPINB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-301 amino acids from the C-terminal region of human SERPINB8.
SERPINB8
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
For WB starting dilution is: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
SERPINB8
(serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))
pi8 antikoerper, cap2 antikoerper, CAP-2 antikoerper, CAP2 antikoerper, NK10 antikoerper, Spi8 antikoerper, ovalbumin antikoerper, PI8 antikoerper, serpin family B member 8 antikoerper, serpin B8 antikoerper, serpin peptidase inhibitor, clade B (ovalbumin), member 8 antikoerper, serine (or cysteine) peptidase inhibitor, clade B, member 8 antikoerper, Serpinb8 antikoerper, SERPINB8 antikoerper, LOC607205 antikoerper, serpinb8 antikoerper, LOC100424017 antikoerper
Hintergrund
The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8, SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).