UNC13B Antikörper (AA 1062-1091)

Produktnummer ABIN5532754

Produktdetails anti-UNC13B Antikörper

Target: UNC13B (Unc-13 Homolog B (UNC13B))

Bindungsspezifität: AA 1062-1091

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC13B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu UNC13B

Target: UNC13B (Unc-13 Homolog B (UNC13B))

Andere Bezeichnung: UNC13B (UNC13B Produkte)

Synonyme: MUNC13 antikoerper, UNC13 antikoerper, Unc13h2 antikoerper, UNC13B antikoerper, Munc13-2 antikoerper, Munc13-1 antikoerper, Unc13a antikoerper, Unc13h1 antikoerper, unc-13 homolog B antikoerper, unc-13 homolog B (C. elegans) antikoerper, UNC13B antikoerper, Unc13b antikoerper

Hintergrund: UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).

Molekulargewicht: 181 kDa

Gen-ID: 10497

UniProt: O14795

Pathways: Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis