UNC13B Antikörper (N-Term)

Produktnummer ABIN657040

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch UNC13B in WB. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für UNC13B Antikörper (N-Term) (ABIN657040)

Target: UNC13B (Unc-13 Homolog B (UNC13B))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC13B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB32155

Produktdetails anti-UNC13B Antikörper

Bindungsspezifität: AA 263-292, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the N-terminal region of human UNC13B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu UNC13B

Target: UNC13B (Unc-13 Homolog B (UNC13B))

Andere Bezeichnung: UNC13B

Hintergrund: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq].

Molekulargewicht: 180679

NCBI Accession: NP_006368

UniProt: O14795

Pathways: Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis